GRK 2 Polyclonal Antibody, 50ul[BT-AP03822] Cell Dissociation Decreased levels of Endophilin B2

Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis

Several transcript variants encoding different isoforms have been found for COPS3

PH (Pleckstrin homology)

possibly through the interaction with beta- and gamma-catenin at adherens junctions

GRK 2 Polyclonal Antibody, 50ul[BT-AP03822] Cell Dissociation Decreased levels of Endophilin B2Beta adrenergic receptor kinase 1 phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. Beta adrenergic receptor kinase 1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of