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Noxa: role in cancer pathogenesis and treatment

Concerned about side effects

doi: 10.1111/jpn.14097

Moreover, using the recognition of the conserved region Fc fragment and the neonatal Fc receptor (FcRn), IgG can escape lysosomal degradation after endocytosis with a half-life of 2 to 3 weeks through the FcRn-mediated recirculation mechanism