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Accordingly, the ES products of several parasites have been mined to characterize the individual constituent molecules with a capacity to interact with, and modulate, the phenotype/function of host macrophages ( Table 1 )

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Combining siramesine and lapatinib causes ferroptosis through iron transport disruption leading to increased ROS in breast cancer [182, 183], or targeting GPX4 might be a potential strategy to enhance antitumor effects of lapatinib in NSCLC cells [184]

With exogenous GH, in-vitro proliferation markers increased and JAK2 was activatedsuggesting a permissive/synergistic interface with GH signaling in this cell type