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Topotecan denosine InChiKey: RIIIVYLDVVJOFM-UHFFFAOYSA-N

Topotecan denosine InChiKey: RIIIVYLDVVJOFM-UHFFFAOYSA-N

Name: Topotecan denosine InChiKey: RIIIVYLDVVJOFM-UHFFFAOYSA-N
Brand: www.cleversources.com
SKU: 95578738936
Price: 96.80 USD
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SKU: 95578738936

4.4

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Topotecan denosine InChiKey: RIIIVYLDVVJOFM-UHFFFAOYSA-NTopocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid

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Description

InChiKey: RIIIVYLDVVJOFM-UHFFFAOYSA-N

(E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide 4-methylbenzenesulfonate

Behrendt HJ

Formula: C9H11IN2O5

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