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NBI-74330 - CAS# 855527-92-3 Size:Solid 10 mg 11bH-cyclohexa[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol

SKU: 88572429231

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NBI-74330 - CAS# 855527-92-3 Size:Solid 10 mg 11bH-cyclohexa[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-olNBI 74330 is an antagonist of CXC chemokine receptor 3 (CXCR3) with IC50 values of 7nM to18nM. NBI 74330 attenuates atherosclerotic plaque formation in LDL receptor deficient mice. Chemokine receptor CXCR3 promotes growth of glioma. CXCR3 antagonism exerts a direct anti glioma effect and this receptor may be a potential therapeutic target for treating human GBM. Product information CAS Number: 855527 92 3 Molecular Weight: 605. 58 Formula:

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Description

11bH-cyclohexa[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol

InChi: InChI=1S/C24H30N2O2

13(19):3143-9

is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5

NBI-74330 - CAS# 855527-92-3 Size:Solid 10 mg 11bH-cyclohexa[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-olNBI 74330 is an antagonist of CXC chemokine receptor 3 (CXCR3) with IC50 values of 7nM to18nM. NBI 74330 attenuates atherosclerotic plaque formation in LDL receptor deficient mice. Chemokine receptor CXCR3 promotes growth of glioma. CXCR3 antagonism exerts a direct anti glioma effect and this receptor may be a potential therapeutic target for treating human GBM. Product information CAS Number: 855527 92 3 Molecular Weight: 605. 58 Formula:

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