ML365 Size:Solid 2 mg 3(34Dihydroxycinnamoyl)quinate
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ML365 Size:Solid 2 mg 3(34Dihydroxycinnamoyl)quinateML365 is a potent and selective K2P3. 1 TASK 1 channel blocker. ML365 blocks TASK1 channels in both the thallium influx fluorescent assay (IC50 = 4 nM) and an automated electrophysiology assay (IC50 = 16 nM). Based on potency differences, it possesses more than 60 fold selectivity for inhibition of TASK1 over a closely related, two pore domain potassium channel, TASK3. ML365 displays little or no inhibition at 30 M of more distantly related potassium
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