ACY-775 1063 dhydrochloride Wnt signaling pathway inhibitor PRI-724

Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB)

Osipova EA

Ferrostatin-1 was used at 0

48(24):7535-43

ACY-775 1063 dhydrochloride Wnt signaling pathway inhibitor PRI-724ACY 775 is a potent and selective histone deacetylase 6 (HDAC6) inhibitor with IC50 of 7. 5 nM. Product information CAS Number: 1375466 18 4 Molecular Weight: 330. 36 Formula: C17H19FN4O2 Chemical Name: 2 ((1 (3 Fluorophenyl)cyclohexyl)amino) N hydroxypyrimidine 5 carboxamide Smiles: ONC(=O)C1C=NC(NC2(CCCCC2)C2=CC=CC(F)=C2)=NC=1 InChiKey: IYBURCQQEUNLDL UHFFFAOYSA N InChi: InChI=1S C17H19FN4O2 c18 14 6 4 5 13(9 14)17(7 2 1 3 8 17)21 16 19 10 12(11 20