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NBMPR - CAS# 38048-32-7 Catalog No.:M7080-2 RIP2 kinase is composed of

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NBMPR - CAS# 38048-32-7 Catalog No.:M7080-2 RIP2 kinase is composed ofNBMPR, CAS No. 38048 32 7, also known as S 4 nitrophenylmethyl 6 thioinosine, is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1. NBMPR is routinely used at concentrations of 0. 10 M and 0. 10 mM to specifically inhibit transport of nucleosides mediated by equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2), respectively. NBMPR at a concentration of 0. 10 mM abolishes ABCG2 activity. Product

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Description

RIP2 kinase is composed of an N-terminal kinase domain and a C-terminal caspase-recruitment domain (CARD) linked via an intermediate (IM) region

PubMed PMID: 25644580

Chemical Name: (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1

7 uM (cellular inhibition of phospho-Ser916-PKD1 activity) [1] Target: PKD CID 2011756

NBMPR - CAS# 38048-32-7 Catalog No.:M7080-2 RIP2 kinase is composed ofNBMPR, CAS No. 38048 32 7, also known as S 4 nitrophenylmethyl 6 thioinosine, is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1. NBMPR is routinely used at concentrations of 0. 10 M and 0. 10 mM to specifically inhibit transport of nucleosides mediated by equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2), respectively. NBMPR at a concentration of 0. 10 mM abolishes ABCG2 activity. Product

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