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ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 302 InChi: InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2

ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 302 InChi: InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2

Name: ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 302 InChi: InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2
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ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 302 InChi: InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2ME0328, CAS No. 1445251 22 8, is a potent, selective and cell permeable PARP 3 inhibitor with IC50 of 0. 89 M. It has good selectivity against PARP 1, PARP 2 and other ARDT enzymes. Enhances CRISPR Cas9 mediated HER2 mutation frequency, resulting in increased reduction in proliferation of HER2 positive breast cancer cells. Product information CAS Number: 1445251 22 8 Molecular Weight: 321. 37 Formula: C19H19N3O2 Chemical Name: (S) 3 (4 oxo 3,4

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InChi: InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2

DMOG was used at 100 µM final concentration in vitro and in cellular assays

InChi: InChI=1S/C20H24ClN3O4S

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