PIK-75 hydrochloride G 149 CAS Number: 431996-53-1

CAS Number: 431996-53-1

5-trifluorophenyl)-

These studies support the potential utility of AMG 837 for the treatment of type 2 diabetes

AT-101 is a small molecule inhibitor of Bcl-2/Bcl-xL/Mcl-1 that potently induces apoptosis in various cancer cell lines

PIK-75 hydrochloride G 149 CAS Number: 431996-53-1PIK 75 was developed as part of a PI 3 kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK 75, administered at 50 mg kg, inhibited the growth of HeLa cell xenografts in mice models. Product information CAS Number: 372196 77 5 Molecular