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SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S It inhibits Wee1 in H3K36me3-deficient

SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S It inhibits Wee1 in H3K36me3-deficient

Name: SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S It inhibits Wee1 in H3K36me3-deficient
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SKU: 73675838702
Price: 45.00 USD
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SKU: 73675838702

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SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S It inhibits Wee1 in H3K36me3-deficientSBI 0206965, CAS No. 1884220 36 3, is a potent and selective autophagy Kinase ULK1 Inhibitor. Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. SBI 0206965 is a highly selective ULK1 kinase inhibitor in vitro and suppressed ULK1 mediated phosphorylation events in cells, regulating autophagy and cell survival. SBI 0206965 greatly synergized with mechanistic target

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Description

It inhibits Wee1 in H3K36me3-deficient cells results in RRM2 reduction

Solubility: DMSO: 2

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

Stat1•Stat3

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