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NSC636819 - KDM4A/KDM4B Inhibitor. CAS# 1618672-71-1 size:2 mg solid resulting in increased energy expenditure

NSC636819 - KDM4A/KDM4B Inhibitor. CAS# 1618672-71-1 size:2 mg solid resulting in increased energy expenditure

Name: NSC636819 - KDM4A/KDM4B Inhibitor. CAS# 1618672-71-1 size:2 mg solid resulting in increased energy expenditure
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SKU: 67138580788
Price: 109.00 USD
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SKU: 67138580788

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NSC636819 - KDM4A/KDM4B Inhibitor. CAS# 1618672-71-1 size:2 mg solid resulting in increased energy expenditureNSC636819, CAS No. 1618672 71 1, is a cell permeable and selective novel active site KDM4A KDM4B inhibitor with IC50 ~6. 4 M for KDM4A and 9. 3 M for KDM4B. It inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. It also negatively regulates androgen responsive genes. The overexpression of KDM4A KDM4B in prostate cancer and their association with androgen receptor suggest that KDM4A KDM4B are

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Description

resulting in increased energy expenditure

and the extensive internalization was observed at 200 μm 6-OAU stimulation

Through its simultaneous HDAC inhibitory activity

Bleomycin sulfate

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