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Folic acid Size:Solid 2 mg combination with the synthetic androgen

SKU: 63567276693

4.8
USD97.60 USD121.60

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Live Spec

Folic acid Size:Solid 2 mg combination with the synthetic androgenABT 100 is an orally bioavailable farnesyltransferase inhibitor. ABT 100 inhibited proliferation of cells in vitro carrying oncogenic H Ras (EJ 1 bladder; IC(50) 2. 2 nmol L), Ki Ras (DLD 1 colon, MDA MB 231 breast, HCT 116 colon, and MiaPaCa 2 pancreatic; IC(50) range, 3. 8 9. 2 nmol L), and wild type Ras (PC 3 and DU 145; IC(50), 70 and 818 nmol L, respectively) as well as clonogenic potential. ABT 100 shows 70% to 80% oral bioavailability in mice.

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Description

combination with the synthetic androgen R1881 in parental LNCaP cells

CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR

InChiKey: OTUBDDRFPQLPKD-UHFFFAOYSA-N

In rabbit isolated ventricular myocytes

Folic acid Size:Solid 2 mg combination with the synthetic androgenABT 100 is an orally bioavailable farnesyltransferase inhibitor. ABT 100 inhibited proliferation of cells in vitro carrying oncogenic H Ras (EJ 1 bladder; IC(50) 2. 2 nmol L), Ki Ras (DLD 1 colon, MDA MB 231 breast, HCT 116 colon, and MiaPaCa 2 pancreatic; IC(50) range, 3. 8 9. 2 nmol L), and wild type Ras (PC 3 and DU 145; IC(50), 70 and 818 nmol L, respectively) as well as clonogenic potential. ABT 100 shows 70% to 80% oral bioavailability in mice.

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