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Specifically, KPV is a fragment of alpha-melanocyte-stimulating hormone (-MSH), a larger peptide with anti-inflammatory, antimicrobial, and fever-reducing properties.1 Even more specifically, the fragment in question is the C-terminal region of -MSH, which is particularly good at neutralizing pathogens.2 While many therapeutic peptides are taken exclusively by needle, KPV stands apart in that it can also be administered as an oral capsule or chewable tablet

doi: 10.1016/j.plaphy.2024.108433 38 IshikawaT.TamakiS.MarutaT.ShigeokaS

ISSN 0379-5721

Peripheral and central immune system crosstalk in Alzheimer diseasea research prospectus