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doi: 10.1016/S0140-6736(08)61206-4 [DOI] [PubMed] [Google Scholar] 116

It is most commonly administered via subcutaneous injection

While a fibrotic matrix initially contributes to tissue repair, after injury, chronic and persistent kidney damage in the development of CKD leads to uncontrolled fibrotic matrix deposition, resulting in reduced blood supply, destruction of normal organ structure, and eventual glomerulosclerosis, renal tubular atrophy, and interstitial fibrosis [9, 10]