Biperiden ROTAC for CDK6 InChi: InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3
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Biperiden ROTAC for CDK6 InChi: InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3AZD8186 is and inhibitor of the beta isoform of phosphoinositide 3 kinase (PI3K), with potential antineoplastic activity. Upon administration, PI3Kbeta inhibitor AZD8186 selectively inhibits the activity of PI3Kbeta in the PI3K Akt mTOR signaling pathway, which may result in a decrease of tumor cell proliferation. It also induces cell death in PI3K expressing cancer cells. By specifically targeting class I PI3K beta, this agent may be more efficacious
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