(R)-Baclofen an D3 Hydrochloride 58(1):419-32

58(1):419-32

Molecular Weight: 465

Chemical Name: 2-((2-((4-methoxyphenyl)amino)pyrimidin-4-yl)amino)ethan-1-ol hydrochloride

Obeticholic acid (INT-747) increases the expression of FXR-regulated genes in rat hepatocytes

(R)-Baclofen an D3 Hydrochloride 58(1):419-32Arbaclofen, also known as (R) Baclofen, D Baclofen and STX209, is a selective GABA B agonist and is hypothesized to modulate the balance of excitatory to inhibitory neurotransmission, and has shown preliminary evidence of benefit in fragile X syndrome. STX209 may be a potentially effective therapy to treat the core symptoms of FXS. Autism spectrum disorder (ASD) is a behaviorally defined disorder which has increased in prevalence over the last two