Pemetrexed (disodium) ium (Chloride) 2015 Nov-Dec

2015 Nov-Dec

S3I-201 significantly reduces viable cell numbers and inhibits growth of transformed mouse fibroblasts NIH 3T3/v-Src and breast carcinoma cell lines (MDA-MB-231

is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M

ML188 provides an excellent starting point for the further design and refinement of 3CLpro inhibitors that act by a noncovalent mechanism of action

Pemetrexed (disodium) ium (Chloride) 2015 Nov-DecPemtrexed disodium is the disodium salt of a synthetic pyrimidine based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2' deoxyuridine 5' monophosphate (dUMP) to 2' deoxythymidine 5' monophosphate (dTMP), an essential precursor in DNA synthesis. Product information CAS Number: 150399 23 8 Molecular Weight: 471. 37 Formula: C20H19N5Na2O6 Synonym: LY231514 disodium Alimta disodium LY