NU7026 - CAS# 154447-35-5 Catalog No.:M112-2S and it raises the possibility

and it raises the possibility that targeting VCP might prevent proteasome inhibitor–resistant tumors from escaping through the aggresome-autophagy pathways and cause them to collapse under the high load of unfolded proteins

3 nM in a radioactive enzyme assay and is over 100-fold selective for other histone methyltransferases/HMTs

CAS Number: 747-36-4

OSI-027 was used at 1-10 µM in vitro and in cellular assays

NU7026 - CAS# 154447-35-5 Catalog No.:M112-2S and it raises the possibilityNU7026, CAS No. 154447 35 5, is a novel specific DNA PK inhibitor with IC50 of 0. 230. 01 M, also inhibits PI3K with IC50 of 133 M. Product information CAS Number: 154447 35 5 Molecular Weight: 281. 31 Formula: C17H15NO3 Chemical Name: 2 morpholino 4H benzo[h]chromen 4 one Smiles: O=C1C=C(OC2=C1C=CC1=CC=CC=C12)N1CCOCC1 InChiKey: KKTZALUTXUZPSN UHFFFAOYSA N InChi: InChI=1S C17H15NO3 c19 15 11 16(18 7 9 20 10 8 18)21 17 13 4 2 1 3 12(13)5 6 14(15)17 h1