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This may be linked to ketones, which are chemicals produced when the body uses fat for energy

Kato S, Funakoshi H, Nakamura T, Kato M, Nakano I, et al

Participants got 0.25 mg of subcutaneous semaglutide weekly for the first 2 weeks, 0.5 mg weekly in weeks 3 and 4, and 1.0 mg weekly from then through week 24