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OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S is a cell permeable and

OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S is a cell permeable and

Name: OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S is a cell permeable and
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SKU: 45933431020
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SKU: 45933431020

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OICR9429 - WDR5 Antagonist. CAS# 1801787-56-3 Catalog No.:M60255-10S is a cell permeable andOICR9429, CAS No. 1801787 56 3, is a potent and selective WD repeat containing protein 5 (WDR5) antagonist (Kd ~24 52 nM). It has >100 fold selectivity over other methyltransferases tested. It disrupts WDR5 interaction with peptide regions of MLL and Histone 3. OICR 9429 also disrupts the interaction of WDR5 with MLL1 and RbBP5 in cells with IC50 values below 1 M. Product information CAS Number: 1801787 56 3 Molecular Weight: 555. 59 Formula:

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Description

is a cell permeable and selective novel active-site KDM4A/KDM4B inhibitor with IC50 ~6

HS Tariff Code: 382200

93 mL/min/kg

It abrogated DNA damaged checkpoints induced by gemcitabine

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