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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Formula: C20H24O4

Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Formula: C20H24O4

Name: Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Formula: C20H24O4
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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Formula: C20H24O4Olcegepant, also known as BIBN 4096 or BIBN 4096BS is is the first potent and selective non peptide antagonist of the calcitonin gene related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary

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Formula: C20H24O4

Eur J Clin Pharmacol

Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O

such as overactivation of the OX1R pathway being associated with panic or anxiety states

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