WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 7(10):e45539

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Abstract DDT02-01: GDC-0068: A novel

CFTR Inhibitor II

RG108 can potentially be used to maintain embryonic stem (ES) cells in an undifferentiated state as well as replace transcription factors in both mouse and human cell reprogramming

WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 7(10):e45539WDR5 0103, CAS No. 890190 22 4, is a potent and selective WD repeat containing protein 5 (WDR5) antagonist with Kd of 450 nM. It has no effect on a panel of seven other methyltransferases, including SETD7. It binds in the WDR5 peptide binding pocket and inhibits the catalytic activity of the MLL core complex in vitro. WDR5 0103 is a good chemical probe to demonstrate inhibition of an important protein protein interaction and form the basis for further