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UBF-1 Polyclonal Antibody, 20ul DNA Fragments Aberrant expression of this gene

SKU: 96869148769

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UBF-1 Polyclonal Antibody, 20ul DNA Fragments Aberrant expression of this geneUBTF encodes a member of the HMG box DNA binding protein family. The nucleolar transcription factor 1 plays a critical role in ribosomal RNA transcription as a key component of the pre initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre rRNA processing, and its activity is regulated by both phosphorylation and acetylation.

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Description

Aberrant expression of this gene may promote tumorigenesis

processing and nuclear export

the activation of transforming growth factor beta

TLN1 encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts

UBF-1 Polyclonal Antibody, 20ul DNA Fragments Aberrant expression of this geneUBTF encodes a member of the HMG box DNA binding protein family. The nucleolar transcription factor 1 plays a critical role in ribosomal RNA transcription as a key component of the pre initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre rRNA processing, and its activity is regulated by both phosphorylation and acetylation.

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