GMIP Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases Spastic paraplegias are a diverse

Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive| lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts

This protease is ATP-dependent and targets specific proteins for degradation

This gene encodes a member of the acyl-coenzyme A binding domain containing protein family

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain

GMIP Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases Spastic paraplegias are a diverseThis gene encodes a member of the ARHGAP family of Rho Rac Cdc42 like GTPase activating proteins. The encoded protein interacts with the Ras related protein Gem through its N terminal domain. Separately it interacts with RhoA through a RhoGAP domain and stimulates RhoA dependent GTPase activity. Alternative splicing results in multiple transcript variants.