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V-ATPase D Polyclonal Antibody, 100ul Enzymes & Activity Assays This gene includes a microsatellite

SKU: 95012770948

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V-ATPase D Polyclonal Antibody, 100ul Enzymes & Activity Assays This gene includes a microsatelliteATP6V1D (ATPase H+ transporting V1 subunit D) encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a

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Description

This gene includes a microsatellite repeat in the coding region

an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced

Their diverse functions include regulating neurotransmitter release| heart rate| insulin secretion| neuronal excitability| epithelial electrolyte transport| smooth muscle contraction| and cell volume

and certain facial and developmental defects

V-ATPase D Polyclonal Antibody, 100ul Enzymes & Activity Assays This gene includes a microsatelliteATP6V1D (ATPase H+ transporting V1 subunit D) encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a

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