CD63 Polyclonal Antibody, 50ul[BT-AP02139] Microplate Mixer The Transcription factor 4 recognizes

The Transcription factor 4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers

a helical hinge region involved in oligomerization

Two transcripts that encode the same protein have been identified for this gene

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CD63 Polyclonal Antibody, 50ul[BT-AP02139] Microplate Mixer The Transcription factor 4 recognizesCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin