Crk-L(Phospho Tyr207) Polyclonal Antibody, 20ul Micro Centrifuge Tubes GIT2 undergoes extensive alternative splicing

GIT2 undergoes extensive alternative splicing to generate multiple isoforms

This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape

This gene has been identified as a tumor suppressor gene in several types of cancer

The p60 subunit acts to sever and disassemble microtubules| while the p80 subunit targets the enzyme to the centrosome

Crk-L(Phospho Tyr207) Polyclonal Antibody, 20ul Micro Centrifuge Tubes GIT2 undergoes extensive alternative splicingThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.