TRPS1 Polyclonal Antibody, 50ul Pipette Controller CDC42 binding protein kinase alpha

CDC42 binding protein kinase alpha encoded by CDC42BPA is a member of the Serine/Threonine protein kinase family

It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor| alpha)| targeting it for degradation and thus activating nuclear factor kappa-B

which translocates to the nucleus to function as a transcription factor

While subunits alpha and beta play a role in complement-mediated bacterial killing

TRPS1 Polyclonal Antibody, 50ul Pipette Controller CDC42 binding protein kinase alphaTRPS1 (transcriptional repressor GATA binding 1) encodes a transcription factor that represses GATA regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in TRPS1 are a cause of tricho rhino phalangeal syndrome (TRPS) types I III.