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MEPE Polyclonal Antibody, 50ul Microplate Mixer CSTF1 encodes one of three

SKU: 87746652284

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MEPE Polyclonal Antibody, 50ul Microplate Mixer CSTF1 encodes one of threeThis gene encodes a secreted calcium binding phosphoprotein that belongs to the small integrin binding ligand, N linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging related trabecular bone loss. Alternative splicing

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Description

CSTF1 encodes one of three subunits which combine to form cleavage stimulation factor (CSTF)

Alternate transcriptional splice variants of CACNA2D4 have been observed but have not been thoroughly characterized

GO annotations related to this gene include nucleic acid binding and transcription factor activity

Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex

MEPE Polyclonal Antibody, 50ul Microplate Mixer CSTF1 encodes one of threeThis gene encodes a secreted calcium binding phosphoprotein that belongs to the small integrin binding ligand, N linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging related trabecular bone loss. Alternative splicing

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