HEXA Polyclonal Antibody, 50ul Cell Culture Dishes This gene is a member

This gene is a member of the type IV| cyclic AMP (cAMP)-specific| cyclic nucleotide phosphodiesterase (PDE) family

and dermatan sulfate

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum

A pseudogene of AURKB is located on chromosome 8

HEXA Polyclonal Antibody, 50ul Cell Culture Dishes This gene is a memberHEXA encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons,