IRS-1(phospho Ser639) Polyclonal Antibody, 50ul Cell Separation and Collection Mutations at this locus have

Mutations at this locus have been associated with Rett syndrome

it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity

Theis gene encodes a member of the fibroblast growth factor (FGF) family

IRS-1(phospho Ser639) Polyclonal Antibody, 50ul Cell Separation and Collection Mutations at this locus haveThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.