HMG-I/HMG-Y (Acetyl Lys15) Rabbit Polyclonal Antibody, 50ul Vacuum Filter A significantly increased expression level

A significantly increased expression level of this gene was observed in tumor-derived cells

and appear to regulate cytoskeletal organization

The heterodimer binds ubiquitinated proteins

The protein encoded by this gene belongs to the Fbws class and| in addition to an F-box| contains multiple WD40 repeats

HMG-I/HMG-Y (Acetyl Lys15) Rabbit Polyclonal Antibody, 50ul Vacuum Filter A significantly increased expression levelThis gene encodes a chromatin associated protein involved in the regulation of gene transcription integration of retroviruses into chromosomes and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT rich regions in double stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.