PXR Polyclonal Antibody, 100ul General Lab Use Alternatively-spliced transcript variants have been

Alternatively-spliced transcript variants have been observed

This complex (anaphase promoting complex subunit 1) is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation

implying different ligand specificity

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family

PXR Polyclonal Antibody, 100ul General Lab Use Alternatively-spliced transcript variants have beenThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including