SIGIR Polyclonal Antibody, 20ul Filtration Binds to GC boxes promoters

Binds to GC boxes promoters elements

is a 348 amino acid protein that is encoded by a gene which maps to chromosome 19

but our experiment always detected a 60-70kDa protein by western blot

The use by some variants of an alternate promoter in an up

SIGIR Polyclonal Antibody, 20ul Filtration Binds to GC boxes promotersActs as a negative regulator of the Toll like and IL 1R receptor signaling pathways. Attenuates the recruitment of receptor proximal signaling components to the TLR4 receptor, probably through an TIR TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin 1 receptor family.,Contains 1 Ig like C2 type (immunoglobulin like) domain.,Contains 1 TIR