ADAM10 Polyclonal Antibody, 50ul PCR Series Defects in EP300 are a

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

are located closely on chromosome 11

elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport

The main portion of the receptor is a heterodimer composed of 2 polypeptide chains

ADAM10 Polyclonal Antibody, 50ul PCR Series Defects in EP300 are aMembers of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 encodes and ADAM family member that cleaves many proteins including TNF alpha and E cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.