TLE1/2/3/4 Polyclonal Antibody, 50ul Plates & Dishes mutations in this gene can

mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy

a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion

meningocerebrovascular amyloidosis

It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates

TLE1/2/3/4 Polyclonal Antibody, 50ul Plates & Dishes mutations in this gene canTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as