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AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes |Contains 1 BTB (POZ) domain

SKU: 65798441687

4.7
PLN162.00 PLN183.00

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AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes |Contains 1 BTB (POZ) domainThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

|Contains 1 BTB (POZ) domain

The encoded protein contains three extracellular C2-like immunoglobulin domains

and was able to prevent apoptosis of motor neurons induced by axotomy

This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones

AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes |Contains 1 BTB (POZ) domainThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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