Smad3 mouse Monoclonal Antibody(1E8), 20ul Bio-Reaction Tube PI3K functions as a heterodimer

PI3K functions as a heterodimer of a regulatory and a catalytic subunit

together with N-terminal extracellular and C-terminal intracellular domains

This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II

This gene encodes a member of the membrane-spanning 4A gene family

Smad3 mouse Monoclonal Antibody(1E8), 20ul Bio-Reaction Tube PI3K functions as a heterodimerThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of