Human Inhibitor of Growth Protein 4, ING4 ELISA Kit, 96T Nucleic Acid Isolation & Purification TP and TP5 may play

TP and TP5 may play a role in T-cell development and function

and can cause renal tubular dysgenesis

Does not inhibit proliferation of myeloid progenitors in colony formation assays

This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus

Human Inhibitor of Growth Protein 4, ING4 ELISA Kit, 96T Nucleic Acid Isolation & Purification TP and TP5 may playComponent of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys 14' (H3K14ac), and have reduced activity toward histone H4 (PubMed: 16387653). Through chromatin acetylation it may function in DNA replication (PubMed: 16387653). May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed: 15251430, PubMed: 15528276). Can suppress brain tumor