CDC42 Polyclonal Antibody, 50ul Electronic Pipette contributes to the activation of

contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases

subunit:Component of multiple ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes formed of CUL5

The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins

and by targeting the same set of genes

CDC42 Polyclonal Antibody, 50ul Electronic Pipette contributes to the activation ofThe protein encoded by this gene is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein.