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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segment

SKU: 5771205827

4.7
USD162.00 USD192.00

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segmentBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

a transmembrane segment

with biallelic

which contains a trinucleotide repeat (CAG) length polymorphism

Multiple alternatively spliced transcript variants encoding the same protein are observed

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segmentBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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