ErbB-3 Polyclonal Antibody, 100ul[BT-AP03039] Antibody Humanization Prominin-1 localizes to membrane protrusions

Prominin-1 localizes to membrane protrusions and is often expressed on adult stem cells

which is involved in axon elongation

Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies

it is believed that it is located at 3p21

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03039] Antibody Humanization Prominin-1 localizes to membrane protrusionsERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation