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A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00055] ssDNA Synthesis This gene is the inferred

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A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00055] ssDNA Synthesis This gene is the inferredADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth

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Description

This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW)

is generated in pathophysiologic conditions such as inflammation

This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton

CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00055] ssDNA Synthesis This gene is the inferredADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth

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