AHR Rabbit Polyclonal Antibody, 20ul Mammalian Expression The encoded protein has also

The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells

Two isoforms of CEP55 are expressed due to alternative splicing events

Conversely| increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives

embryogenesis

AHR Rabbit Polyclonal Antibody, 20ul Mammalian Expression The encoded protein has alsoThe protein encoded by this gene is a ligand activated helix loop helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.