SRA1 Rabbit Polyclonal Antibody, 100ul Stepper BNIP3 is silenced in tumors

BNIP3 is silenced in tumors by DNA methylation

such as epithelial cells

Two transcript variants encoding different isoforms have been identified

This protein may also play a role in growth a differentiation of certain cancer cells

SRA1 Rabbit Polyclonal Antibody, 100ul Stepper BNIP3 is silenced in tumorsBoth long non coding and protein coding RNAs are transcribed from this gene and they represent alternatively spliced transcript variants. This gene was initially defined as a non coding RNA which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non NR activities including metabolism adipogenesis and chromatin organization. The