PUMA Polyclonal Antibody, 20ul Antisense Oligonucleotides RCC2/TD-60 is a member of

RCC2/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors

not all of them are fully characterized

a disease caused by degeneration of the cerebellum

High levels of this protein and RIP3 are associated with inflammatory bowel disease in children

PUMA Polyclonal Antibody, 20ul Antisense Oligonucleotides RCC2/TD-60 is a member ofBBC3 encodes a member of the BCL 2 family of proteins. This family member belongs to the BH3 only pro apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti apoptotic Bcl 2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro apoptotic role, BBC3 is a potential drug target for cancer