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Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays phospholipase C gamma 1 has

SKU: 41321345829

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Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays phospholipase C gamma 1 hasRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

phospholipase C gamma 1 has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

The gene mutation results in primary NAA deficiency (hypoacetylaspartia)

Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described

The human gene is both the structural and functional homolog of the yeast scERV1 gene

Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays phospholipase C gamma 1 hasRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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