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Pim-1 Polyclonal Antibody, 50ul Lysosome May act as a motor

SKU: 37538166244

4.1
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Pim-1 Polyclonal Antibody, 50ul Lysosome May act as a motorThe protein encoded by PIM1 (Pim 1 proto oncogene, serine threonine kinase) belongs to the Ser Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both

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Description

May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules

cytosolic and mitochondrial

These heterogeneous aggregates consist of 30-40 subunits| the alpha-A and alpha-B subunits have a 3:1 ratio

This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein

Pim-1 Polyclonal Antibody, 50ul Lysosome May act as a motorThe protein encoded by PIM1 (Pim 1 proto oncogene, serine threonine kinase) belongs to the Ser Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both

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