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IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulation

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IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulationThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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Description

May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles

NDUFS5 is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family

therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development

Over-expressed in breast cancer

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulationThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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